The Skinny on Ultrathin DES: Meta-analysis Shows Some Long-term Advantages
May 19, 2021 Compared with second-generation DES, devices with ultrathin struts are associated with less TLF, driven by reductions in clinically driven TLR, a long-term meta-analysis of multiple RCTs suggests. The thinner struts have been thought to offer advantages in terms of producing less inflammation, vessel injury, neointimal proliferation, and thrombus formation. The new meta-analysis builds on the findings of a prior meta-analysis showing that ultrathin-strut DES were associated with a lower risk of TLF (composite of cardiac death, MI, or clinically driven TLR) at 1 year compared with...