Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV
Researchers identify ACE2 as the functional receptor of the two close relatives of MERS-CoV, NeoCoV and PDF-2180-CoV, in bats.
Source: news-medical.net
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Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants
In a new study, researchers identified conserved sites in the SARS-CoV-2 spike protein using structural and sequence data, and then combined the results with existing deep mutational scanning data to design six antigens that can offer protection against significant immune escape mutations in the SARS-CoV-2 receptor-binding domain.
Source: news-medical.net
Novel SARS-CoV-2 mutations reported in chronic HIV patients
A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.
Source: news-medical.net
Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective
A recent study published in the journal Science brings a detailed chemical and molecular perspective on the improved evasion of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the retention of strong interactions with the receptor as two principal factors underneath the notorious transmissibility of the SARS-CoV-2 Omicron variant.
Source: news-medical.net
Study suggests SARS-CoV-2 Omicron variant spike mediated immune escape and tropism shift
A new study showed that the SARS-CoV-2 Omicron spike binds to its receptor with enhanced affinity and yet evades vaccine-elicited neutralizing antibodies and that a booster mRNA vaccine broadened the neutralization of Omicron.
Source: news-medical.net