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"Disease-causing mutations in the small heat shock protein Hsp27 alter " by Anthea Rote - Vimarsana News

"Disease-causing mutations in the small heat shock protein Hsp27 alter " by Anthea Rote

Charcot Marie Tooth disease (CMT) and distal hereditary motor neuropathy (dHMN) are two heterogeneous and clinically overlapping diseases of the peripheral nervous system. Pathogenic mutations in various proteins including the small heat shock protein 27 (Hsp27, HSPB1) are associated with CMT and dHMN; however the molecular mechanisms underlying disease progression are not understood. Hsp27 is a ubiquitously expressed and highly conserved molecular chaperone that is involved in cytoprotective functions including protein homeostasis (proteostasis), redox modulation, inhibition of apoptosis, sta...

Source: uow.edu.au
International team determines structure of a key player in antibiotic resistance - Vimarsana News

International team determines structure of a key player in antibiotic resistance

UTSW computational biologist uses machine learning to help determine 3D structure of Type IV Secretion System.

BBCNEWS BBC News June 4, 2024 01:13:00 - Vimarsana News

BBCNEWS BBC News June 4, 2024 01:13:00

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Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM - Vimarsana News

Researchers report near-atomic-resolution images of nitrogenase during catalysis using cryo-EM

Previously, it has been impossible to capture the high-resolution images of nitrogenase, the only enzyme capable of reducing nitrogen into ammonia, during catalytic action.

First-of-its-kind technology repairs and regenerates heart muscle cells - Vimarsana News

First-of-its-kind technology repairs and regenerates heart muscle cells

Researchers at the University of Houston are reporting a first-of-its-kind technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically known.