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BOSTON--(BUSINESS WIRE)--Emulate, Inc., the leading provider of next-generation in vitro models, today announced the publication “Integrating Liver-Chip Data into Pharmaceutical Decision-Making Processes” in Expert Opinion on Drug Discovery. The article introduces a decision-making framework that includes two guidel...
BOSTON--(BUSINESS WIRE)--Sep 15, 2023--
This illustration shows a 3D printed heart ventricle engineered with fiber-infused ink. Credit: Harvard SEAS By Kat J. McAlpine / SEAS Communications Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures. Their goals include creating better in vitro platforms for discovering new therapeutics for heart disease, the leading cause of death in the United States, responsible for about one in every five deaths nationally, and using 3D-printed cardiac tissues to evaluate which treatments might work best in individual patie...
A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.
T cell bispecific antibodies (TCBs) are an emerging class of immunotherapeutics with several TCBs approved by the FDA for the treatment of leukemias, lymphomas, and myelomas. TCBs label tumor cells with one of their ends, and attract immune cells with another end to coerce them into tumor cell killing. However, one major challenge in the development of TCBs are “on-target, off-tumor” toxicities at sites in the body that also express TCB-targeted antigens. A new collaboration of Jennifer Lewis’ group and researchers from the Roche Innovation Centers in Switzerland and Germany now created ...