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"A Comparison of In Vivo Bone Tissue Generation Using Calcium Phosphate" by D. S.Abdullah Al Maruf, Kai Cheng et al.

Autologous bone replacement remains the preferred treatment for segmental defects of the mandible; however, it cannot replicate complex facial geometry and causes donor site morbidity. Bone tissue engineering has the potential to overcome these limitations. Various commercially available calcium phosphate-based bone substitutes (Novabone®, BioOss®, and Zengro®) are commonly used in dentistry for small bone defects around teeth and implants. However, their role in ectopic bone formation, which can later be applied as vascularized graft in a bone defect, is yet to be explored. Here, we compare the above-mentioned bone substitutes with autologous bone with the aim of selecting one for future studies of segmental mandibular repair. Six female sheep, aged 7–8 years, were implanted with 40 mm long four-chambered polyether ether ketone (PEEK) bioreactors prepared using additive manufacturing followed by plasma immersion ion implantation (PIII) to improve hydrophilicity and bioactivity. E ....

3d Printed , Bone Substitute , Polyether Ether Ketone , Ascularized Periosteum ,

Scaling-up iPS spheroid culture production

AMSBIO introduces the ABLE 3D Magnetic Stir and Disposable Bioreactor System, a cost-effective solution for lab-scale induced pluripotent stem (iPS) cell spheroid culture production. Click to read more. ....

Magnetic Stir , Disposable Bioreactor System ,