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A high-dose version of the opioid reversal spray naloxone, made by Hikma Pharmaceuticals, did not result in an increased survival rate compared with lower-dose versions of the drug when administered...
The analysis also suggests that those given the higher 8 milligram strength spray were more than twice as likely to experience opioid withdrawal symptoms compared to other sprays such as Narcan that use a 4 mg dose. The Hikma version, sold under the brand name Kloxxado, was approved in 2021 after U.S. Food and Drug Administration advisers and National Institutes of Health reports suggested that a high-dose version was needed to respond to overdoses by more potent opioids such as fentanyl. The U.S. opioid epidemic has caused more than a half million overdose deaths over more than two decades,...
The FDA has approved a shelf-life extension for Emergent Biosolutions’ Narcan (naloxone hydrochloride) Nasal Spray products from 3 years to 4 years.
Coborn’s, Inc. has announced that over-the-counter Narcan nasal spray, an opioid overdosing reversal drug, is now available at all Coborn’s, Cash Wise Foods, and Marketplace Foods grocery stores at the
Coborn’s, Inc. announces over-the-counter Narcan nasal spray, an opioid overdosing reversal drug, is now available at all Coborn’s, Cash Wise Foods, and Marketplace Foods grocery stores at the Guest Services