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Study Shows How Amyloid Beta Forms in Brain Nerve Cells


Study Shows How Amyloid Beta Forms in Brain Nerve Cells
by Colleen Fleiss on 
May 19, 2021 at 11:42 PM
A new study has uncovered how amyloid beta the neurotoxin linked to Alzheimer s disease (AD) - forms in axons and related structures that connect neurons in the brain, where it causes the most damage.
The findings by Massachusetts General Hospital (MGH) researchers, published in Cell Reports, could serve as a guidepost for developing new therapies to prevent the onset of this devastating neurological disease.
Among his many contributions to research on AD, Rudolph Tanzi, PhD, vice chair of Neurology and co-director of the McCance Center for Brain Health at MGH, led a team in 1986 that discovered the first Alzheimer s disease gene, known as APP, which provides instructions for making amyloid protein precursor (APP). ....

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