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Press Release


New study published in Cell Press demonstrates that SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W. | May 3, 2023 ....

Branka Horvat , Centre International De Recherche En Infectiologie , Press Release , Cell Press , Euronext Paris , Centre International De Recherche , Geneuro Sa Stock Exchange , Press Release , Roinflammatory Gnro Ch0308403085 ,

GeNeuro: Researchers Detect HERV-W ENV in COVID-19 Patients and Link Expression to Disease Severity


GeNeuro: Researchers Detect HERV-W ENV in COVID-19 Patients and Link Expression to Disease Severity
Data published in the Lancet s EBioMedicine shows that the pathogenic envelope protein of the human endogenous retrovirus W (HERV-W ENV) is found on lymphocytes of hospitalized patients with COVID-19, and that its level of expression is associated with disease severity.
HERV-W ENV s pro-inflammatory properties thought to act as an accelerant of the activation of the innate immune system, fueling the severity of COVID-19 evolution and impacting long term recovery.
Preliminary data available on Research Square also shows HERV-W ENV expression in lymphocytes following in vitro exposure to SARS-CoV-2 in about 20% of healthy blood donors, suggesting individual susceptibility. ....

United States , Chris Maggos , Nicolas Merigeau , Institut Pasteur , Claudia Matteucci , Louis Victor Delouvrier Mathilde Bohin , Mike Sinclair , Branka Horvat , Tor Vergata School Of Medicine , University Of Rome Tor Vergata , International Center , International Center Infectiology , Karolinska Institutet Academic Specialist Center , French National Research Agency , National Research Council , Infectiology Research In Lyon , Italian Space Agency , Department Of Experimental Medicine , Research Square , Infectiology Research , Euronext Paris , Experimental Medicine , Chief Scientific Officer , Multiple Sclerosis , Karolinska Institutet , Academic Specialist Center ,