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Although we’ve learned a lot about autism over the past few decades, there’s still a great deal to discover. One of the more recent findings involves the human microbiome.
The biological roots of autism continue to perplex researchers, despite a growing body of studies looking at an increasing array of genetic, cellular and microbial data.
The collection of microbes that inhabit the human gut has been shown to play a role in autism, but the mechanics of this link have remained awash in ambiguity. Taking a fresh computational approach to the problem, a study published today in Nature Neuroscience sheds new light on the relationship between the microbiome and autism.
As riot police moved in on a so-called “freedom convoy” in Ottawa on Saturday, protesters ...
A study comparing mice engineered to synthesize the metabolite 4EPS, to mice that cannot, shows the metabolite passes into the brain and dampens maturation of oligodendrocytes, thinning the myelin insulation around axons. This results in anxiety-like behavior in mice that can be reversed by drugs that promote myelination. In an accompanying human study, the authors show a drug that adsorbs 4EPS from the human gut alleviates anxiety in adolescents with autism.