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Post-HCT Cyclophosphamide Boosts Transplant Success


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Increased access to allogeneic hematopoietic cell transplant (HCT) is feasible for patients who lack an HLA-matched donor with the use of post-transplant cyclophosphamide (PTCy), according to a prospective phase II study.
Use of PTCy resulted in an overall survival rate of 76% at 1 year, as well as a low incidence of severe acute graft-versus-host-disease (GVHD), in patients almost half of whom were ethnic minorities who did not have a well-matched donor in the family or in donor registries, reported Bronwen Shaw, MD, PhD, of the Center for International Blood and Marrow Transplantation Research, Medical College of Wisconsin in Milwaukee, and colleagues. ....

United States , Bronwen Shaw , National Marrow Donor Program , International Blood , College Of Wisconsin , Marrow Transplantation Research , Medical College , New England Journal , Clin Oncol , ஒன்றுபட்டது மாநிலங்களில் , ப்ரோன்வென் ஷா , தேசிய மஜ்ஜை நன்கொடையாளர் ப்ரோக்ர்யாம் , சர்வதேச இரத்தம் , கல்லூரி ஆஃப் விஸ்கான்சின் , மருத்துவ கல்லூரி , புதியது இங்கிலாந்து இதழ் ,