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Some particle size instruments, known as single particle counters, measure individual particle size, while others measure surface area as a function of particle size. Further instruments measure mass or volume versus size, while others still measure multiple functions of scattered light intensity as a function of size. Each of these instruments can generate particle size distributions and, in theory, one can transform between types in order to correlate the results. In practice, if a measurement with a single particle counter generated a differential number-weighted size distribution, how wo...

Using Dynamic Light Scattering (DLS) to Analyze Virus Particles Conventional visual techniques of detecting virus particles in solution provide a glimpse of an extremely small sampling volume, while the method of particle analysis employing dynamic light scattering generates an ensemble average of particles inside the solutions. Virus particles incubated in the laboratory pose an issue, as they need to be grown inside cells in a media containing albumin and additional small proteins, like those inside Fetal Bovine Serum (FBS) or Minimum Essential Media (MEM) solutions. When virus particles a...

Using Dynamic Light Scattering (DLS) to Analyze Virus Particles Conventional visual techniques of detecting virus particles in solution provide a glimpse of an extremely small sampling volume, while the method of particle analysis employing dynamic light scattering generates an ensemble average of particles inside the solutions. Virus particles incubated in the laboratory pose an issue, as they need to be grown inside cells in a media containing albumin and additional small proteins, like those inside Fetal Bovine Serum (FBS) or Minimum Essential Media (MEM) solutions. When v...