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New research from the University of California, Irvine reveals how the circadian regulation of glucose production in the liver is lost during lung cancer progression, and how the resulting increase in glucose production may fuel cancer cell growth. ....
Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected. Unfortunately, some patients still experience poor outcomes after surgical resection, prompting further research on the relationship between a patient s preoperative status and the likelihood of good postoperative outcomes. Given this need for information, Dr. Shinya Tanaka from the Department of Rehabilitation and Prof. Naoki Ozeki from the Department of Thoracic Surgery, Nagoya University, and their colleagues decided to investigate. Previous studies had identified some risk factors for mortality after NSCLC resection, including sarcopenia, which is defined as the progressive loss of muscle mass and strength and predominantly occurs in old ....
email article A lot of anecdotal evidence reveals that the second dose of vaccine knocks many out for a bit. Watch the video to see ZDoggMD s experience with his second shot. Following is a rough transcript of his remarks (Note: errors are possible): So that second coronavirus shot, it is a doozy. And I ll tell you, I say that from personal experience. I was knocked on my a by that thing. So the first shot I got, Moderna, blew it off, a little sore arm, no big deal, right? The second shot, a month later eight hours after the shots happened I was having fevers, shaking, chills muscle aches felt like I got hit by a train. Throbbing headache, couldn t sleep. The arm was like red and swollen. I was just behaving like a complete diva, like, you know, telling Mrs. Dogg, oh, woe is me. ....
Researchers use cachexia model to assess cancer-derived myocardial impairments Oncotarget recently published Evaluation of cancer-derived myocardial impairments using a mouse model which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder. Using the mouse cachexia model that they established previously, the authors investigated myocardial damage in tumor-bearing mice. When rat cardiomyoblasts were treated with mouse cachexia model ascites and subjected to flux analysis, both oxidative phosphorylation and glycolysis were suppressed, and the cells were in a quiescent state. These results are in good agreement with those previously reported on cancerous myocardial damage. ....