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Pegcetacoplan for PNH More Cost-Effective Than Anti-C5 Monoclonal Antibodies

A cost-utility analysis conducted from the perspective of the Italian health system found that pegcetacoplan was more effective and less costly than 2 complement 5 (C5) inhibitors for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). ....

Outcomes Research , European Organisation For Research , Italian National Health Service , Italian National Health , European Organisation , Cancer Core Quality , Life Questionnaire , Rare Blood ,

Nirogacestat Linked With Improved Functional Status in Patients With Desmoid Tumors

Results presented at the National Community Oncology Dispensing Association International Spring Forum describe meaningful improvements in functioning among patients who received the oral gamma secretase inhibitor to treat progressing desmoid tumors. ....

United States , Nirogacestat Ogsiveo , International Spring Forum , European Organisation For Research , National Community Oncology Dispensing Association , Image Credit , Monkey Business , Physical Functioning , European Organisation , Cancer Core Quality , Life Questionnaire , Role Functioning , North America , Desmoid Tumors , Soft Tissue Sarcoma ,

Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval

This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical ....

United States , San Diego , Aarons Kesselheim , Commonwealth Fund , American Association For Cancer Research Annual Meeting , Division Of Pharmacoepidemiology , National Clinical Trial , Leukemia Lymphoma Society , Drug Administration , European Organisation For Research , Section Ref , Key Regulatory , Data Extraction , Approval Determinations , Quality Of Life Data , Google Scholar , European Organisation , Cancer Core Quality , Regulatory Outcome , Regular Approval , Microsoft Excel , Year Outcomes , Accelerated Approval , Drs Liu , Interest Disclosures , Lymphoma Society ,

Telehealth, e-Health Psychological Interventions Potentially Promote Sexual Health in CRC

Patients with colorectal cancer (CRC) could participate in telehealth and e-health interventions to promote their sexual health, although efficacy of these interventions needs to be further studied. ....

Sexual Health , European Organization For Research , Cochrane Library , Beck Depression Inventory , Dyadic Adjustment Scale , Dyadic Sexual Communication Scale , European Organization , Cancer Core Quality , Life Questionnaire , Intimacy Enhancement , Psychoeducational Intervention , Cancer Survivors , Survivorship Intervention Sexual Health , Quality Assessment Tool , Quantitative Studies ,

FDA Approves Capivasertib Plus Fulvestrant in Advanced HR+/HER2– Breast Cancer With PIK3CA, AKT1, or PTEN Alterations

The FDA has approved capivasertib plus fulvestrant for the treatment of patients with HR-positive, HER2-negative, locally advanced or metastatic breast cancer harboring 1 or more PIK3CA, AKT1, or PTEN alteration, following progression on at least 1 endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy. ....

European Organization For Research , Olivier Le Moal , European Organization , Cancer Core Quality , Life Questionnaire , Breast Cancer , Capivasertib With Fulvestrant ,