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New Blood Test Predicts COVID-9 Recovery by Karishma Abhishek on  January 17, 2021 at 6:27 PM Developing sudden failure of organs that leads to various complications like respiratory or kidney inefficiency or requiring other intensive care remains one of the challenging aspects of COVID-19 that may cause death even in young patients. With an aim to explore which hospitalized patients can get into such complications, involving nearly 100 patients newly admitted to the hospital with COVID-19, a simple and rapid blood test has been formulated by scientists at Washington...

One of the most vexing aspects of the COVID-19 pandemic is doctors' inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care.

Researchers Ram Sagar Misra, Shailja Singh and Anand Ranganathan NEW DELHI: Over the years, tuberculosis and malaria have developed resistance to most drugs, including antibiotics. That has been because most drug research focuses on targeting the pathogen — the TB bacteria or malaria parasite. Now, 22 researchers from JNU and BHU have shifted focus to the host cells which are infected and isolated a molecule that can help counter drug-resistant TB and malaria. What they have done is use the pathogens’ defence mechanisms against itself. “Intracellular pathogens hijack essential host int...

Newly discovered biochemical pathway can protect cells from ferroptosis The hallmarks of cancer include rapid cell-reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death. To circumvent these negative consequences of supercharged growth, cancer cells stimulate pathways to reduce oxidative stress and avoid cell death. In an article published in Cell Metabolism, Moffitt Cancer Center researchers report on a newly discovered biochemical pathway that protects cells from a type of cell death called ferroptosis. Ferr...

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response. A new study published in Cell shows that endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection. Researchers suggest this mechanism could open new avenues for turning on the immune sys...