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Cell Migration and Invasion Assays by Platypus Technologies In order to ensure consistent cell-free regions for each experiment, Cell Migration and Invasion Assays by Platypus Technologies utilize exclusion zone technology. The Oris™  Cell Migration and Invasion Assays allow the reproducible and accurate quantification of cell movement. Cell Migration Assays No artificial membranes Industry-standard 96- or 384-well formats Image Credit: Platypus Technologies, LLC In order to form a central cell-free detection zone in the center of every well of a 96-well plate, Oris™ Cell Migration assay...

Cell Migration Assays by Platypus Technologies Cell Migration Assays from Platypus Technologies utilize exclusion-zone technology, ensuring that results are high quality and ideal for publication. Researchers in both pharmaceutical companies and academia will benefit from the use of robust, powerful Cell Migration Assays by Platypus Technologies, particularly in studies looking to advance cancer research, drug discovery, or wound healing. Cell Migration Assays from Platypus Technologies offer a range of benefits, including: Industry-standard 96- or 384-well formats Monitoring in real-time Doe...

ECM Integrity Assay In order to test the integrity of each assay’s ECM, 100 µg/mL of Collagen Type I – FITC conjugate (Sigma-Aldrich) was coated onto wells of an Oris™ assay plate (without stoppers) and a Costar ® plate. These plates were then incubated overnight at 37 °C / 5% CO 2. After incubation, stoppers were inserted into the Oris™ assay plate while sterile PBS was added to both assay plates’ wells. At 1 hour, 24 hour, and 48 hour intervals post-insertion, stoppers were removed before fluorescence images were acquired using a Zeiss Axiovert inverted microscope. Scratches we...

Mathematical modeling is a tool with the potential to uncover fine detail of the complex cell signaling networks involved in managing the eukaryotic cell cycle.

COVID-19 and lung cancer have a common pathway, say researchers The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide. With over 2.4 million deaths, this virus can cause severe disease in certain high-risk groups such as those with metabolic syndrome, diabetes, cardiovascular disease and an abnormally high body mass in...