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IMAGE: Left - a schematic of the long form of the tracrRNA used by the CRISPR-Cas9 system in bacteria; Right - the standard guide RNA used by many scientists as part.
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Credit: Joshua Modell, Rachael Workman and Johns Hopkins Medicine
In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 as a genetic dimmer switch for CRISPR-Cas9 genes. Its role of dialing down or dimming CRISPR-Cas9 activity may help scientists develop new ways to genetically engineer cells for research purposes. ....

United States , Erika Smith , Suzanne Sebald , Leonardo Graeff , Marie Stoltzfus , Johns Hopkins , Joshua Modell , Binh Nguyen , Emory University , Johns Hopkins University School Of Medicine , Weill Cornell Medical College , Nobel Prize , Johns Hopkins University School , Rachael Workman , Teja Pammi , Chad Euler , Weill Cornell Medical , Medicine Health , ஒன்றுபட்டது மாநிலங்களில் , எரிகா ஸ்மித் , ஸுஸ்யாந் செபால்ட் , லியோனார்டோ க்ராெப்ப் , மேரி ஸ்த்தொல்திஜுபுச் , ஜான்ஸ் ஹாப்கின்ஸ் , ஜோஷுவா மாடல் , பின் ஂக்யந் ,