Live Breaking News & Updates on Children Brain Tumor Tissue Consortium

Stay updated with breaking news from Children brain tumor tissue consortium. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Proteomics analysis IDs potential drug targets for aggressive cancers

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful. ....

United States , Baylor College Of Medicine , Darshans Chandrashekar , Yiqun Zhang , Diana Monsivais , Sooryanarayana Varambally , Yasmin Vasquez , Ramyap Masand , Fengju Chen , Johnc Faver , Michaele Scheurer , Martinm Matzuk , Burroughs Wellcome Fund , University Of Texas Md Anderson Cancer Center , National Institutes Of Health , Clinical Proteomic Tumor Analysis Consortium , Researchers At Baylor College Of Medicine , University Of Alabama At Birmingham , Cancer Prevention Research Institute Of Texas , Children Brain Tumor Tissue Consortium , Danl Duncan Comprehensive Cancer Center , Cancer Genome Atlas Consortium , Baylor College , Chad Creighton , Cancer Bioinformatics , Texas Children ,

Proteomics analysis identifies potential drug targets for aggressive human cancers

E-Mail
Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets. They report in the journal
Oncogene, the identification of proteomic signatures that are associated with clinical measures of aggressive disease for each of the seven cancer types studied. Some signatures were shared between different types of cancer and included cellular pathways of altered metabolism. Importantly, experimental results provided proof-of-concept that their proteomics analysis approach is a valuable strategy to identify potential therapeutic targets.
There are two notable aspects of this study. One is that we explored the proteomic landscape of cancer looking for proteins that were expressed in association with aggressive forms of cancer, said co-corresponding author Dr. Chad Creighton, professor of medicine and co-director of Cancer Bio ....

United States , Baylor College Of Medicine , Darshans Chandrashekar , Yiqun Zhang , Diana Monsivais , Sooryanarayana Varambally , Yasmin Vasquez , Ramyap Masand , Fengju Chen , Johnc Faver , Michaele Scheurer , Martinm Matzuk , Burroughs Wellcome Fund , University Of Texas Md Anderson Cancer Center , National Institutes Of Health , Clinical Proteomic Tumor Analysis Consortium , Researchers At Baylor College Of Medicine , University Of Alabama At Birmingham , Cancer Prevention Research Institute Of Texas , Children Brain Tumor Tissue Consortium , Danl Duncan Comprehensive Cancer Center , Cancer Genome Atlas Consortium , Baylor College , Chad Creighton , Cancer Bioinformatics , Texas Children ,