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DEAR MAYO CLINIC: I've dealt with migraine attacks for years. So has my mom. I typically manage by using over-the-counter pain medication that includes caffeine as soon as my symptoms begin. Then, if my migraine doesn't improve, I use a prescription triptan medication. But my headache days have been increasing, and my doctor suggested I try a newer preventive migraine medication. Can you please explain more about medication options?

Triptans, ergots, and antiemetics are the most effective classes of medications for migraine, according to a study published.

New research found that triptans, ergots, and antiemetics are more effective at treating migraines compared to ibuprofen. Acetaminophen, the active ingredient in Tylenol, was nearly 20% less effective at treating migraines than ibuprofen.

Three classes of drugs could be 2 to 5 times more effective than ibuprofen for the treatment of migraine attacks, according to results of a study.

For many people with migraine, it can be difficult to find a treatment that is effective and reliable, and information on how medications compare to one another is lacking.