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Gut microbiota acts like an auxiliary liver, study finds

Gut microbiota acts like an auxiliary liver, study finds
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Chun-jun-guo , Friedman-center , Jill-roberts-institute-for-research , Cell-host , Weill-cornell-medicine , Jill-roberts-institute , Inflammatory-bowel-disease , Weill-cornell ,

Dietary fiber promote inflammation in gut: Research

Researchers have discovered that a dietary fiber known as inulin, which is used in health supplements and has some anti-inflammatory qualities, can also encourage an allergy-related kind of inflammation in the gut and lungs as well as other parts of the body.

New-york , United-states , Cornell-university , Mohammad-arifuzzaman , Frank-schroeder , David-artis , Weill-cornell , Chun-jun-guo , Friedman-center , Department-of-chemistry , Jill-roberts-institute-for-inflammatory-bowel-disease , Cornell-university-ithaca

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

New-york , United-states , Mohammad-arifuzzaman , Frank-schroeder , David-artis , Weill-cornell , Chun-jun-guo , Emily-henderson , Friedman-center , Department-of-chemistry , Study-co , College-of-arts

Study: Dietary fibre promote allergy-related type of inflammation in lung, gut

Previous studies have found that inulin boosts populations of beneficial gut bacterial species which in turn boost levels of anti-inflammatory immune cells called regulatory T (Treg) cells.In this new study, the researchers examined inulin`s effects more comprehensively. 

New-york , United-states , New-delhi , Delhi , India , Mohammad-arifuzzaman , Frank-schroeder , David-artis , Weill-cornell , Chun-jun-guo , Friedman-center , Department-of-chemistry

Study finds dietary fibre promote allergy-related type of inflammation in lung, gut

According to researchers, a type of dietary fibre called inulin, which is used in health supplements and have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, as well as other parts of the body.

New-york , United-states , Mohammad-arifuzzaman , Frank-schroeder , David-artis , Weill-cornell , Chun-jun-guo , Friedman-center , Department-of-chemistry , College-of-arts , Boyce-thompson-institute-on-cornell-ithaca , Boyce-thompson-institute

Study finds dietary fibre promote allergy-related type of inflammation in lung, gut

According to researchers, a type of dietary fibre called inulin, which is used in health supplements and have certain anti-inflammatory properties, can also pro

New-york , United-states , Washington , Mohammad-arifuzzaman , Frank-schroeder , David-artis , Weill-cornell , Chun-jun-guo , Friedman-center , Department-of-chemistry , College-of-arts , Boyce-thompson-institute-on-cornell-ithaca

Study finds 'Achilles heel' of Crohn's-linked bacteria


February 11, 2021
The discovery of an “Achilles’ heel” in a type of gut bacteria that causes intestinal inflammation in patients with Crohn’s disease may lead to more targeted therapies for the difficult-to-treat disease, according to researchers at Weill Cornell Medicine and NewYork-Presbyterian.
In a study published Feb. 5 in Cell Host and Microbe, the investigators showed that patients with Crohn’s disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), which
promotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of the intestine, triggering inflammation.

Kenneth-simpson , Sloan-kettering , Weill-cornell , Monica-viladomiu , Gretchen-diehl , Ellen-scherl , Randy-longman , Maeva-metz , Jill-roberts-center , Division-of-gastroenterology , Jill-roberts-institute-for-research , Cornell-college-of-veterinary-medicine

Discovery of 'Achilles heel' in gut bacteria may lead to targeted therapies for Crohn's disease


Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease
The discovery of an "Achilles heel" in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.
In a study published Feb. 3 in
Cell Host and Microbe, the investigators showed that patients with Crohn's disease have an overabundance of a type of gut bacteria called adherent-invasive Escherichia coli (AIEC), which promotes inflammation in the intestine. Their experiments revealed that a metabolite produced by the bacteria interacts with immune system cells in the lining of the intestine, triggering inflammation. Interfering with this process, by either reducing the bacteria's food supply or eliminating a key enzyme in the process relieved gut inflammation in a mouse model of Crohn's disease.

Weill-cornell , Monica-viladomiu , Ellen-scherl , Maeva-metz , Sloan-kettering , Randy-longman , Emily-henderson , Jill-roberts-center , Division-of-gastroenterology , Jill-roberts-institute-for-research , Presbyterian-weill-cornell-medical-center , Longman