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Forendo Pharma Successfully Completes Phase 1 Studies of FOR-6219 in Endometriosis, Aiming to Advance Program into Phase 2 Clinical Studies


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Forendo Pharma, a clinical-stage drug development company focusing on novel treatments in women s health, today announced the completion of Phase 1 studies in healthy volunteers for its lead development program in endometriosis, FOR-6219, and provided a development outlook. The successfully concluded Phase 1 program demonstrated that FOR-6219, a HSD17B1 enzyme-targeting small-molecule, was safe and well-tolerated and delivered additional results supporting Forendo s therapeutic concept. The company is now planning the Phase 2 program including endometriosis patients in the US.
The now completed Phase 1 program delivered an initial body of tolerability, safety and pharmacokinetic data. For chronic endometriosis treatment, tolerability and a lack of systemic estrogen deficiency-related side effects are of the utmost importance as we see current therapies struggling to be widely adopted due to their side effect profiles. A local effect on the target tissue with our intr ....

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WellmarkerBio receives approval for Phase I clinical trial from the Australian Therapeutic Goods Administration


WellmarkerBio receives approval for Phase I clinical trial from the Australian Therapeutic Goods Administration
SEOUL, South Korea, March 3, 2021 /PRNewswire/ Wellmarker Bio(www.wmbio.co) announced that on February 23, 2021 the company received approval from the Australian Therapeutic Goods Administration (TGA) for a Phase I clinical trial using WM-S1-030, a targeted anti-cancer drug for colorectal cancer and progressive cancer.
Under the approval, Wellmarker Bio will seek to recruit a total of 100 advanced cancer patients in multiple centers, including sites in Australia such as the Linear Clinical Center and Monash Hospital, to conduct clinical trials in two stages: Phase Ia (dose escalation) and Phase Ib (dose expansion). We plan to study the drug s safety at various doses in Phase Ia, and in Phase Ib, we will conduct studies for indication expansion as well as combination therapy with chemotherapy, other targeted or cancer immunotherapy drugs along with validation o ....

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Apervita, Diameter Health join forces to improve data quality for value-based care contracting


Apervita, Diameter Health join forces to improve data quality for value-based care contracting
Health IT company Apervita will leverage Diameter Health s capabilities which include cleaning and enriching clinical data to enhance data quality for stakeholders looking to create value-based care contracts.
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A new health IT partnership aims to improve clinical data quality and thereby increase the volume of data available for care quality measurement.
The partnership will combine Chicago-based Apervita and Farmington, Connecticut-based Diameter Health’s expertise to provide payers, providers and other healthcare stakeholders with access to clean clinical data for value-based care delivery, said Rick Howard, Apervita’s chief product officer, in an email. ....

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Welcome To IANS Live - LatestNews - Covaxin demonstrates interim clinical efficacy of 81%


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Hyderabad, March 3 (IANS) Bharat Biotech on Wednesday announced the first interim analysis of Covaxin, which shows the efficacy of the Covid-19 vaccine to be at 81 per cent.
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Update: 03-March-2021 ....

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