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Objective To investigate potential interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at global level. Design Two stage time series analysis. Setting 372 cities across 19 countries and regions. Population Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease. Main outcome measure Daily mortality data during 1994-2020. Stratified analyses by co-pollutant exposures and synergy index (>1 denotes the combined effect of pollutants is greater than individual effects) were applied to explore the interaction between PM2.5 and O...

Objective To evaluate lag-response associations and effect modifications of exposure to floods with risks of all cause, cardiovascular, and respiratory mortality on a global scale. Design Time series study. Setting 761 communities in 35 countries or territories with at least one flood event during the study period. Participants Multi-Country Multi-City Collaborative Research Network database, Australian Cause of Death Unit Record File, New Zealand Integrated Data Infrastructure, and the International Network for the Demographic Evaluation of Populations and their Health Network database. Main ...

Betty Thomason ended her summer on a high note: raising funds for Parkinson’s research by scaling the heights of Mount Kilimanjaro. She climbed in honor of her father, who was diagnosed with the disease in 2020.

In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative dis...

/PRNewswire/ -- Tune in to The Balancing Act on Monday, February 20, 2023 at 7:30am (ET/PT) to watch their Rare Disease Day Special, featuring Lennox-Gastaut...