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Study Findings May Improve Diagnosis of Vitamin D Deficiency

Investigators of the study aimed to determine whether the analytical performance specifications of 24,25(OH)2D could be generated. ....

Valerii Honcharuk , Nicholas Harvey , Committee Of Scientific Advisors , Committee For Bone Metabolism , National Health Nutrition Examination , Laboratory Medicine , International Osteoporosis Foundation , Lifecourse Epidemiology Centre , University Of Southampton , University Of Li , International Federation Of Clinical Chemistry , International Federation , Clinical Chemistry , Bone Metabolism , European Biological Variation Study , Vitamind Metabolite Ration , Epidemiology Centre , Scientific Advisors , National Health Nutrition Examination Surveys ,

IFCC-IOF study investigates harmonization of assays for ß-CTX

IFCC-IOF study investigates harmonization of assays for ß-CTX
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Clin Chim Acta , Nicholas Harvey , International Osteoporosis Foundation , Committee For Bone Metabolism , Committee Of Bone Markers , Committee Of Scientific Advisors , Laboratory Medicine , International Federation Of Clinical Chemistry , Tissue International , Joint Committee , Bone Marker Standards , International Federation , Clinical Chemistry , Calcified Tissue International , Sheffield United Kingdom , Professor Etienne Cavalier , Bone Markers , Scientific Advisors , Multicenter Study , Evaluate Harmonization , C Terminal Telopeptides , Typei Collagen , Bone Metabolism , Calcif Tissue Int , கிளினிக் சிம் ஆக்டா , நிக்கோலஸ் ஹார்வி ,

IOF and IFCC review calls for harmonization of assays for reference bone turnover markers

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Bone turnover markers (BTMs) in blood and urine are useful tools in monitoring osteoporosis treatment effects and may be useful for improving patient adherence.
In 2011, a Joint Committee on Bone Metabolism of the International Osteoporosis Foundation (IOF) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) designated Procollagen type I N-propeptide (PINP) and the C-terminal telopeptide of type I collagen (β-CTX) in blood as reference bone turnover markers for bone formation and bone resorption, respectively, in osteoporosis. However, the effective clinical implementation of these recommendations requires the standardization/harmonization of commercial assays [1].
As well as a review of the structures of PINP and β-CTX molecules, the authors provide a succinct, referenced summary of current commercial assays, their descriptions, and performance characteristics. Key characteristics and performance specifications of the fou ....

Clin Chim Acta , Samuel Vasikaran , Nicholas Harvey , Committee For Bone Metabolism , International Osteoporosis Foundation , Committee Of Bone Markers , Committee Of Scientific Advisors , Laboratory Medicine , International Federation Of Clinical Chemistry , Committee On Bone Metabolism , Joint Committee , Bone Metabolism , International Federation , Clinical Chemistry , Professor Samuel Vasikaran , Etienne Cavalier , Bone Markers , Scientific Advisors , Clin Chim , Medicine Health , Internal Medicine , Metabolism Metabolic Diseases , Orthopedic Medicine , Pharmaceutical Chemistry , கிளினிக் சிம் ஆக்டா , சாமுவேல் வாசீகரன் ,