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Study finds the biosimilar ABP 654 and ustekinumab do not have clinical meaningful differences according to the step-wide totality-of-evidence approach and thus have similar psychochemical and biological properties.
Supporting Therapeutic Antibody Development with Fc Receptor Affinity Testing Sponsored Content by ACROBiosystemsDec 23 2020 Antibodies are also referred to as immunoglobulins (Ig). Immunoglobulins are large Y-shape proteins that are primarily created by plasma cells. These generally consist of two identical light chains and two identical heavy chains, which are connected by disulfide bonds. Five types of mammalian Ig heavy chain exist and the type of heavy chain present will dictate the class of antibody; for example, IgA, IgD, IgE, IgG, and IgM, respectively. Figure 1. Five different classe...