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Testosterone-replacement therapy noninferior to placebo for preventing cardiovascular events - Vimarsana News

Testosterone-replacement therapy noninferior to placebo for preventing cardiovascular events

1. In this randomized controlled trial, in adults with hypogonadism and cardiovascular risk factors, testosterone did not reduce the incidence of major adverse cardiac events (MACE) compared to a control. 2. Arrhythmias, atrial fibrillation, acute kidney injury, and pulmonary embolism occurred more frequently in the testosterone group. Evidence Rating Level: 1 (Excellent) Study Rundown: Male

Early detection and treatment of postpartum hemorrhage reduces associated complications - Vimarsana News

Early detection and treatment of postpartum hemorrhage reduces associated complications

1. In this randomized controlled trial, the E-MOTIVE bundle, consisting of early detection and treatment of postpartum hemorrhage, was associated with a lower risk of complications than usual care. 2. The E-MOTIVE treatment bundle also resulted in higher detection rates of postpartum hemorrhage and treatment adherence compared to usual care. Evidence Rating Level: 1 (Excellent)

#VisualAbstract: Cyclophosphamide-tacrolimus-mycophenolate mofetil is an effective prophylaxis against graft-versus-host disease - Vimarsana News

#VisualAbstract: Cyclophosphamide-tacrolimus-mycophenolate mofetil is an effective prophylaxis against graft-versus-host disease

1. In this randomized controlled trial, cyclophosphamide-tacrolimus-mycophenolate mofetil was associated with lower rates of graft-versus-host disease (GVHD) compared to tacrolimus-methotrexate in patients undergoing hematopoietic stem-cell transplantation (HSCT). 2. There were no significant differences between groups for overall survival. Evidence Rating Level: 1 (Excellent) Study Rundown: GVHD is a major complication of HSCT. The combination of

Adults with mpox have relatively low JYNNEOS vaccination rates - Vimarsana News

Adults with mpox have relatively low JYNNEOS vaccination rates

1. In this case-control study, adults with mpox were less likely to have been partially or fully vaccinated with the JYNNEOS vaccine compared to those without. 2. The adjusted effectiveness of the JYNNEOS vaccination amongst participants with two doses was estimated to be 66%. Evidence Rating Level: 2 (Good) Study Rundown: Mpox is a viral

Hyperuricemia, Gout Linked to Increased Mortality Risk in Heart Failure - Vimarsana News

Hyperuricemia, Gout Linked to Increased Mortality Risk in Heart Failure

An analysis of NHANES data is offering clinicians an overview of associations between hyperuricemia and gout with increased risk of mortality in patients with heart failure.