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#VisualAbstract: Microaxial Flow Pumps Reduces Mortality But Increases Adverse Events Compared to Standard Care For Cardiogenic Shock

#VisualAbstract: Microaxial Flow Pumps Reduces Mortality But Increases Adverse Events Compared to Standard Care For Cardiogenic Shock
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#VisualAbstract: Empagliflozin does not significantly reduce the risk of heart failure or death in patients after acute myocardial infarction

Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Minute-medicine-inc , Acute-myocardial-infarction , Empagliflozin , Heart-failure , Studygraphics ,

Microaxial flow pump improves infarct-related cardiogenic shock outcomes

1. In this randomized controlled trial, in patients with infarct-relate cardiogenic shock, death from any cause was lower in the group that received the microaxial flow pump compared to the group that received the standard care. 2. The composite safety endpoint occurred in more patients in the microaxial flow pump group than in the standard

Minute-medicine-inc , Rating-level , Confidence-interval , Cardiogenic-shock , Cardiology , Emergency , Infarct-related-cardiogenic-shock , Microaxial-flow-pump , Stemi ,

#VisualAbstract: Sentinel-node biopsy only is noninferior to completion of axillary lymph node dissection in breast cancer with sentinel-node metastases

1. The hazard ratio for recurrence or death comparing sentinel node biopsy only to completion axillary lymph node dissection was non-significant (0.89) and below the noninferiority margin. 2. The overall survival rates at 5 years were similar between both groups, 92.9% vs 92%. Evidence Rating Level: 1 (Excellent) Study Rundown: Previous studies have challenged the necessity

Minute-medicine-inc , Rating-level , Axillary-dissection , Sentinel-node , Ymph-node-metastasis , Axillary-lymph-node-dissection , Breast-cancer , Cancer , Completion-axillary-lymph-node-dissection , Lymph-node , Sentinel-lymph-node-biopsy

Beta-blockers do not lower mortality after myocardial infarction with preserved ejection fraction

1. In this randomized controlled trial, long-term beta-blockers did not impact all-cause mortality among patients with preserved left ventricular ejection fraction (LVEF) following an acute myocardial infarction (MI) and early angiography. 2. Long-term beta-blocker therapy was not associated with a higher risk of adverse events compared to no beta-blocker. Evidence Rating Level: 1 (Excellent) Study

Minute-medicine-inc , Rating-level , Confidence-interval , Beta-blocker , Cardiology , Chronic-disease , Mortality , Myocardial-infarction , Preserved-ejection-fraction ,

#VisualAbstract: Computerized provider order entry prompts can reduce empiric extended-spectrum antibiotic use in patients hospitalized with urinary tract infection

Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Minute-medicine-inc , Antibiotic-therapy , Antibiotics , Empiric-antibiotics , Extended-spectrum-antibiotics , Inspire , Multidrug-resistant-organisms , Urinary-tract-infection , Uti , Studygraphics ,

Semaglutide improves obesity-related heart failure symptoms

1. In this randomized controlled trial, semaglutide was more effective in reducing heart failure-related symptoms and physical limitations in patients with obesity-related heart failure and type 2 diabetes mellitus (T2DM) than placebo. 2. Patients with obesity-related heart failure and T2DM exhibited greater weight loss with semaglutide than placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Heart

United-states , Minute-medicine-inc , Rating-level , Semaglutide-treatment-effect , Heart-failure , Preserved-ejection-fraction , Diabetes-mellitus , Kansas-city-cardiomyopathy-questionnaire , Confidence-interval , Cardiology , Chronic-disease

Minimally invasive surgery provides functional benefit in acute supratentorial intracerebral hemorrhage

1. In this randomized controlled trial, patients who underwent minimally invasive surgical evacuation of a hematoma followed by medical management had lower disability scores than those who received medical management alone. 2. This effect was attributable primarily to intervention for lobar hemorrhages rather than hemorrhages in the basal ganglia. Evidence Rating Level: 1 (Excellent) Study

Minute-medicine-inc , Rating-level , Early-minimally-invasive-removal , Intracerebral-hemorrhage , Bayesian-credible-interval , Acute-supratentorial-intracerebral-hemorrhage , Emergency , Minimally-invasive-surgery , Neurology , Surgery ,

#VisualAbstract: Addition of metronidazole is nonsuperior to conventional antibiotic prophylaxis in preventing pelvic cellulitis and pelvic abscess after total laparoscopic hysterectomy

Click here to read this study in JMIG. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute

Minute-medicine-inc , Antibiotics , Cellulitis , Female , Laparoscopic-hysterectomy , Laparoscopic-surgery , Metronidazole , Pelvic-abscess , Postoperative-care , Studygraphics ,

Humanetics Corporation: BIO 300 Synthetic Genistein Nanosuspension May Protect Against Negative Effects Of Radiation Therapy In Lung Cancer Patients

BIO 300 use led to reduced levels of a proinflammatory/profibrotic cytokine associated with lung injury from radiation therapy. BIO 300 did not interfere with the pharmacokinetics of chemotherapy, did not result in dose limiting toxicities, and led to only mild-moderate adverse events. The Latest A recent multicenter phase 1b/2a clinical trial funded by the National

United-states , Americans , National-institute-of-health , Company-history , Humanetics-corporation , Minute-medicine-inc , National-institute , Transformation-growth-factor ,