Troubled immune system a driver of common eye disease in horses - review
A complex interplay of several dysregulated mechanisms related to the immune system appears responsible for the development of equine recurrent uveitis (ERU), according to the authors of a review. The immune-mediated disease affects the eyes of horses around the world, ultimately leading to blindness. It is characterized by painful, inflammatory bouts alternating with periods of quiescence (causing no trouble or symptoms). During the course of the disease, both eyes can eventually be affected and, since blind horses pose a threat to themselves and their surroundings, affected animals are ofte...