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Morgan Wagner was gifted Endo as a child. At the age of 8, he was diagnosed with an autoimmune condition called Equine Recurrent Uveitis. By the age of 13, he was totally blind.
A complex interplay of several dysregulated mechanisms related to the immune system appears responsible for the development of equine recurrent uveitis (ERU), according to the authors of a review. The immune-mediated disease affects the eyes of horses around the world, ultimately leading to blindness. It is characterized by painful, inflammatory bouts alternating with periods of quiescence (causing no trouble or symptoms). During the course of the disease, both eyes can eventually be affected and, since blind horses pose a threat to themselves and their surroundings, affected animals are ofte...
Horsetalk.co.nz Researchers look to the gut in investigating debilitating eye condition in horses Scientists have found no evidence of changes in the gut bacteria of horses that may be a factor in equine recurrent uveitis, but say more research in the area is warranted. Equine recurrent uveitis is an immune-mediated disease characterized by recurrent episodes of inflammation within the eye. The condition has an estimated prevalence of 1 to 2% in the United States. Despite being a major cause of blindness in horses worldwide, the exact cause remains unknown. Equine recurrent uveitis s...