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An ion pump to deliver chemotherapy agents to the brain


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IMAGE: An ion pump can deliver cytostatics more accurately in the brain, which gives less severe adverse effects in chemotherapy.
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Credit: Thor Balkhed
Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumours. Researchers at Linköping University, Sweden, and the Medical University of Graz, Austria, have shown in cells in culture that an ion pump can deliver drugs more accurately, which gives less severe adverse effects in chemotherapy. The results have been published in Advanced Materials Technologies.
This is the first time an ion pump has been tested as a possible method to treat malignant brain tumours. We used cancer cells in the lab, and the results are extremely promising. However, it will probably take five to ten years before we see this new technology used in treatments for brain tumours , says Daniel Simon, associate professor at th ....

Maria Seitanidou , Silke Patz , Marta Nowakowska , Daniel Simon , Tamara Tomin , Sophie Honeder , Marie Jake , Meysam Karami Rad , Ruth Birner Gruenberger , Linda Waldherr , Tony Schmidt , Rainer Schindl , Danielt Simon , Nassim Ghaffari Tabrizi Wizsy , Joachim Distl , Martin Asslaber , Magnus Berggren , University Of Graz , Alice Wallenberg Foundation , Department Of Science , Laboratory Of Organic Electronics , Austrian Science Fund , Swedish Foundation For Strategic Research , Medical University , Advanced Materials , Organic Electronics ,

Biosensors monitor plant well-being in real time


Credit: Thor Balkhed
Researchers at Linköping University, Sweden, have developed biosensors that make it possible to monitor sugar levels in real time deep in the plant tissues - something that has previously been impossible. The information from the sensors may help agriculture to adapt production as the world faces climate change. The results have been published in the scientific journal
iScience.
The primary source of nutrition for most of the Earth s population is mainly plants, which are also the foundation of the complete ecosystem on which we all depend. Global population is rising, and rapid climate change is at the same time changing the conditions for crop cultivation and agriculture. ....

Danielt Simon , Eriko Gabrielsson , Jeewoong Lee , Totte Niittyl , Eleni Stavrinidou , Tayebeh Abedi , Magnus Berggren , Chiara Diacci , European Union Horizon , Alice Wallenberg Foundation , Laboratory Of Organic Electronics , Wallenberg Wood Science Center , Swedish Research Council , Department Of Science , Plant Science Centre , Swedish Strategic Research Area , Swedish Foundation For Strategic Research , Organic Electronics , European Union , Swedish Foundation , Strategic Research , New Functional Materials , Vivo Xylem Sap Glucose , Plant Sciences , Chemistry Physics Materials Sciences , Superconductors Semiconductors ,