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High Temperatures Reduce Feeding, Neural Circuit Unraveled

High Temperatures Reduce Feeding, Neural Circuit Unraveled
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Sweden , Swedish , Tibor-harkany , Swedish-research-council , Novo-nordisk-foundation , Swedish-research ,

Sweden and US strengthen cooperation on research, innovation and education

To improve the conditions for cooperation between Swedish and American universities, research institutions and businesses on research, innovation a...

San-francisco , California , United-states , Sweden , American , Swedish , Ebba-busch , Swedish-research-council , Vinnova-silicon-valley-office , Industry-ebba , Education-mats , Nordic-innovation-house

Popular diabetes drugs not linked to thyroid cancer risk, study finds

Drugs known as GLP-1 analogs have become increasingly popular to treat diabetes and obesity, but there have been concerns that they might increase the risk of thyroid cancer.

Norway , Sweden , Solna , Stockholm , Denmark , Swedish , Peter-ueda , Karolinska-institutet , Department-of-medicine , Swedish-cancer-society , Swedish-research-council , Cancer

Glucagon-like peptide 1 receptor agonist use and risk of thyroid cancer: Scandinavian cohort study

Objective To investigate whether use of glucagon-like peptide 1 (GLP1) receptor agonists is associated with increased risk of thyroid cancer.

Design Scandinavian cohort study.

Setting Denmark, Norway, and Sweden, 2007-21.

Participants Patients who started GLP1 receptor agonist treatment were compared with patients who started dipeptidyl peptidase 4 (DPP4) inhibitor treatment, and in an additional analysis, patients who started sodium-glucose cotransporter 2 (SGLT2) inhibitor treatment.

Main outcome measures Thyroid cancer identified from nationwide cancer registers. An active-comparator new user study design was used to minimise risks of confounding and time related biases from using real world studies of drug effects. Cox regression was used to estimate hazard ratios, controlling for potential confounders with propensity score weighting.

Results The mean follow-up time was 3.9 years (standard deviation 3.5 years) in the GLP1 receptor agonist group and 5.4 years (standard deviation 3.5 years) in the DPP4 inhibitor group. 76 of 145 410 patients (incidence rate 1.33 events per 10 000 person years) treated with GLP1 receptor agonists and 184 of 291 667 patients (incidence rate 1.46 events per 10 000 person years) treated with DPP4 inhibitors developed thyroid cancer. GLP1 receptor agonist use was not associated with increased risk of thyroid cancer (hazard ratio 0.93, 95% confidence interval 0.66 to 1.31; rate difference −0.13, 95% confidence interval −0.61 to 0.36 events per 10 000 person years). The hazard ratio for medullary thyroid cancer was 1.19 (0.37 to 3.86). In the additional analysis comparing the GLP1 receptor agonist group with the SGLT2 inhibitor group, the hazard ratio for thyroid cancer was 1.16 (0.65 to 2.05).

Conclusions In this large cohort study using nationwide data from three countries, GLP1 receptor agonist use was not associated with a substantially increased risk of thyroid cancer over a mean follow-up of 3.9 years. In the main analysis comparing GLP1 receptor agonists with DPP4 inhibitors, the upper limit of the confidence interval was consistent with no more than a 31% increase in relative risk.

No additional data available. The data analysed in this study were based on Scandinavian nationwide register. Individual level data from the registers can only be accessed through secure servers and only export of aggregated data, as presented in research articles, is allowed. Permission to access data can be made only after fulfilling specific requirements to safeguard the anonymity of the study participants and other data safety issues. For these reasons, data cannot be made generally available.

Norway , Denmark , France , United-states , Sweden , Danish , French , Swedish , Karolinska-institutet , Eli-lilly , Drottning-victorias-frimurarestiftelse , Konung-gustaf

Beta-blockers are often given unnecessarily, a study finds – "This will affect future practice"

Patients who have suffered a minor heart attack do not benefit from beta-blockers, according to a major new study that may change guidelines for cardiac care.

New-zealand , Estonia , Uppsala , Uppsala-lan , Sweden , Swedish , Martin-risenfors , Karolinska-institutet , Tomas-jernberg , Department-of-clinical-sciences , Lung-foundation , Swedish-research-council

Beta Blockers May Not Benefit Many Heart Attack Survivors

Study suggests routine use is likely unnecessary for those with normal ejection fraction

Estonia , Sweden , Stockholm , New-zealand , Swedish , Troels-yndigegn , Swedish-research-council , Swedish-heart-lung-foundation , Lund-university , American-college-of-cardiology-annual-scientific-session , Stockholm-county-council , American-college

Preventive angioplasty does not improve prognosis

Preventive angioplasty does not improve prognosis
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Boston , Massachusetts , United-states , Uppsala , Uppsala-lan , Sweden , Danderyd , Stockholm , Swedish , Karolinska-institutet , Uppala-university , Karolinska-university-hospital

Cardiac Health: Is Treating Specific Heart Artery For Heart Attacks Sufficient?

The study underscores the overall effectiveness of contemporary drug therapies in managing heart attack patients. TheHealthSite.com

Sweden , Stockholm , Boston , Massachusetts , United-states , Swedish , Karolinska-university-hospital , Uppsala-clinical-research-center-at-university , Swedish-research-council , Boston-scientific , Cardiac-health

Vinnova: Swedish proposal for indicative national guidelines for responsible internationalisation

Sweden is heavily dependent on collaborations with the outside world for development and prosperity. Three authorities are now submitting proposals for how internationalisation within research, innovation and education can take place while protecting Sweden's national interests.

Sweden , Swedish , College-council , Swedish-research-council ,

Twins Study Sheds Light on In-Womb Immune Defence

Twins Study Sheds Light on In-Womb Immune Defence
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Huddinge , Stockholm , Sweden , Swedish , Karolinska-institutet , Jonna-bister , Swedish-cancer-society , Centre-for-innovative-medicine-at-karolinska-institutet , European-union-horizon , Alice-wallenberg-foundation , Swedish-society-for-medical-research , Novo-nordisk-foundation