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One antibody can block the dengue virus from causing disease in mice, a study shows. The finding could lead to more effective treatments and a vaccine.

One antibody can block the ability of the dengue virus to cause disease in mice, researchers have found. The findings open the potential for developing effective treatments and designing a vaccine for dengue and similar diseases. Dengue virus, a member of a group of viruses called flaviviruses, causes 50 to 100 million cases of dengue disease each year, with no effective treatment or vaccine. Other members of this group include the viruses that cause Zika, yellow fever, and West Nile fever. As reported in Science, an antibody called 2B7 neutralizes one specific protein the virus makes—a pr...

Date Time Share New research reveals how one antibody blocks dangerous effects of dengue virus infection, offering a potential path to prevention Researchers have revealed how one antibody (in green) is able to neutralize a protein that is central to the dengue virus’s ability to cause disease, by blocking the protein’s ability to interact with host cells. Image credit: Rajani Arora, U-M Life Sciences Institute A team of researchers has discovered an antibody that blocks the ability of the dengue virus to cause disease in mice. The findings open the potential for developing effective tre...