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UAB researchers identify cell-surface marker that indicates fate of T cells - Vimarsana News

UAB researchers identify cell-surface marker that indicates fate of T cells

Published: August 15, 2023

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

Source: news-medical.net
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United StatesLa JollaDiegoo SialerRyanj McmonigleDavid FiggeKellym ChandlerAdamj GetzlerYohsuke HaradaMatthewe PipkinAndrewr SchroederLily RamseyOlaf KutschFangming ZhuEmilyr BrownBraxtond GreerXianyou XiaUniversity Of Alabama At BirminghamScripps Research InstituteDepartment Of Medicine Division Infectious DiseasesDepartment Of MicrobiologyNational Institutes Of HealthUniversity Of Alabama At Birmingham CenterNature CommunicationsTokyo University Of ScienceDepartment Of Pathology
A fate determination fork-in-the-road for germinal center Tfh and T memory cells - Vimarsana News

A fate determination fork-in-the-road for germinal center Tfh and T memory cells

Published: August 14, 2023

Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells. Fangming...

Source: uab.edu
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United StatesLa JollaSteve WoodhuSteve WoodfollicularMatthewe PipkinAndrewr SchroederAdamj GetzlerOlaf KutschDiegoo SialerXianyou XiaYohsuke HaradaBraxtond GreerFangming ZhuRyan McmonigleEmilyr BrownDavid FiggeRyanj McmonigleKellym ChandlerJolla Institute For ImmunologyNational Institutes Of HealthTokyo University Of ScienceScripps Research InstituteDepartment Of Medicinedivision Infectious DiseasesUniversity Of Alabama At Birmingham CenterDepartment Of Microbiology