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Chinese scientists develop new ultra precise gene-editing tool

Hong Kong, May 31: A team of Chinese researchers has developed a new gene-editing tool that differs in approach to the most popular CRISPR-Cas9 gene-editing therapy, saying the new method is ultra-precise, safe and has potential to treat some genetic diseases, the media reported on Wednesday. ....

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Chinese scientists develop new 'ultra precise' gene-editing tool

Hong Kong: A team of Chinese researchers has developed a new gene-editing tool that differs in approach to the most popular CRISPR-Cas9 gene-editing ....

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Developed: New 'ultra precise' gene-editing tool

A team of Chinese researchers has developed a new gene-editing tool that differs in approach to the most popular CRISPR-Cas9 gene-editing therapy, saying the new method is ultra-precise, safe and has potential to treat some genetic diseases. ....

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CRISPR doubles lifespan of mice with rapid ageing disease progeria

ALVIN TELSER/SCIENCE PHOTO LIBRARY
CRISPR gene editing has been used to more than double the lifespan of mice engineered to have the premature ageing disease progeria, also greatly improving their health.
The results far surpassed expectations. Progeria affects many different organs in the body, and the team behind the work didn’t expect that correcting the mutation in a relatively low proportion of cells – 10 to 60 per cent – would have such a big effect. “We were quite amazed,” says David Liu at Harvard University.
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Hutchinson-Gilford progeria syndrome is a rare condition caused when a mutation, which probably took place in the testes or ovaries of a child’s parents, results in a single DNA letter change in one of the two copies of the gene for the lamin A protein. This leads to the production of an abnormal protein called progerin that interferes with cell division and causes many symptoms of premature ageing. The average lifespan of ch ....

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