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Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function without changes in food intake or daily activity. ....
After being placed on high-fat diets, mice were either selected to take the PDE9 inhibiting oral drug or a placebo. The PDE9 inhibitor reduced total ....