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OBX-115 With Acetazolamide Induces Safe and Durable Antitumor Responses in Advanced Melanoma

OBX-115 was well tolerated and produced durable antitumor responses in patients with immune checkpoint inhibitor (ICI)-resistant advanced melanoma. ....

United States , San Diego , Lifileucel Amtagvi , Rodaben Amaria , Department Of Melanoma Medical Oncology , University Of Texas Md Anderson Cancer Center , Division Of Cancer Medicine , Melanoma Medical Oncology , Cancer Medicine , Cancer Center , Obx 115 ,

SD-101 With Immune Checkpoint Inhibition Generates Positive Results in Uveal Melanoma Liver Metastasis

Treatment with SD-101 distributed via pressure-enabled drug delivery with immune checkpoint inhibition was tolerated and resulted in the depletion of Tregs, M-MDSCs, and M2 macrophages in liver metastases in patients with uveal melanoma. ....

San Diego , United States , Sapna Patel , Melanoma Fellowship Program , Department Of Melanoma Medical Oncology , University Of Texas Md Anderson Cancer Center , Uveal Melanoma Program , Melanoma Medical Oncology , Cancer Center , Esd 101 , M Mdscs , Pressure Enabled Drug Delivery , 2023 Sitc Annual Meeting , Phase 1 Perio 01 Trial ,

Texas Medical Center Working On Potential Cancer Breakthrough

Texas Medical Center Working On Potential Cancer Breakthrough
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Texas Medical Center , United States , New York , Baylor College Of Medicine , William Decker , Husseina Tawbi , Todd Pieper , Md Anderson Cancer Center , Department Of Melanoma Medical Oncology , University Of Texas Md Anderson Cancer Center , Houston Chronicle , Baylor College , Melanoma Medical Oncology , Cancer Center , Medical Center , New York City ,

Nivolumab Plus Relatlimab Demonstrates Consistent Benefit for Patients with Advanced Melanoma

Two-year follow-up data from the RELATIVITY-047 trial showed a continued benefit for patients with previously untreated, unresectable, or metastatic melanoma receiving nivolumab plus relatlimab vs nivolumab monotherapy supporting the use of the combination. ....

United States , Husseina Tawbi , Department Of Melanoma Medical Oncology , University Of Texas Md Anderson Cancer Center , Melanoma Medical Oncology , Melanoma Amp Skin Cancer , Skin Cancer , Immunotherapy In Melanoma , Immuno Oncology ,

Dr Tawbi on Nivolumab Plus Relatlimab in Metastatic Melanoma

Hussein A. Tawbi, MD, PhD, discusses the 2-year findings from the phase 2/3 RELATIVITY-047 trial of nivolumab plus relatlimab in treatment-naïve patients with metastatic or unresectable melanoma. ....

United States , Husseina Tawbi , University Of Texas Md Anderson Cancer Center , Department Of Melanoma Medical Oncology , Division Of Cancer Medicine , Personalized Cancer Therapy , Melanoma Medical Oncology , Cancer Medicine , Cancer Center , The University Of Texas Md Anderson Cancer Center , Relativity 047 Trial , Nivolumab Plus Relatlimab , Patients With Metastatic Or Unresectable Melanoma ,