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Cancer Patient Sees Total Remission with Cell Therapy Created by CU Anschutz Scientists


Clinical trial uses CAR-T cells made steps away at the Gates Biomanufacturing Facility
A new clinical trial at the University of Colorado Anschutz Medical Campus, using cells genetically engineered by medical faculty to fight stubborn cancers, is showing encouraging results.
Created at the Gates Biomanufacturing Facility a few steps from CU Anschutz, the chimeric antigen receptor T cells, or CAR-T cells, are being infused into patients with difficult to treat or frequently recurring cancers at UCHealth University of Colorado Hospital.
Heather Pidcoke was among
the locally produced
now has no cancer symptoms.
It’s the first cellular immunotherapy project where the developmental science, regulatory filing and approvals, manufacturing process and infusion of patients in clinical trials have all been done at CU Anschutz. ....

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CRISPR improves method for studying gene functions


Date Time
CRISPR improves method for studying gene functions
Since the genetics revolution, biologists have been working to understand the roles that individual genes play, often with the help of advanced techniques.
One such method, mosaic analysis, has led to many discoveries of the functions of genes. Although mosaic analysis has been widely used in Drosophila, a popular model organism, it is much harder to implement in other organisms.
A new paper describes a technique called Mosaic Analysis by gRNA-induced Crossing-over (MAGIC), which uses CRISPR/Cas9 gene editing technology to make mosaic analysis much simpler. Though the proof-of-principle experiment was done in fruit flies (Drosophila), it can theoretically work in any organism where CRISPR methods apply. ....

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Council support is music to ears of Maleny singer


Sunshine Coast Council
Maleny local Natalie Gauci is among 11 Sunshine Coast region creative arts workers to share in more than $65,000 in Regional Arts Development Funding (RADF).
The 2007 Australian Idol winner received $5,000 for the development of her new album, ‘Pictures of Mars’.
Other successful applications included music and theatre development as well as a diverse range of screen and interdisciplinary projects.
Podcasting was a popular developmental area with two projects, ‘an adaption of A Girl’s Guide to War’ and pilot series, ‘That old queer’, netting more than $14,000 in funding.
Natalie who was also a contestant in The Voice in 2020 said the album was in the early development stages and would comprise nine songs for release over a four-month period alongside an online TV show and launch event in Caloundra on 28 February. ....

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