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[Full text] TRIM11 Promotes Proliferation, Migration, Invasion and EMT of Gastric
TRIM11 Regulates β-Catenin Pathway in vitro and in vivo To explore the underlying mechanism by which TRIM11 regulates gastric cancer, we did some literature research and found that several TRIM proteins can regulate β-catenin pathway, so we hypothesize that TRIM11 may regulate GC through β-catenin pathway. We detected the expression level of β-catenin in TRIM11 overexpression in MGC-803 cells and found that it was increased. Then, we further investigated the expression level of β-catenin downstream molecules and found that CyclinD1 and C-myc were upregulated and Axin2 were downregulated ...
Source: dovepress.com