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"Conformance of a 3T radiotherapy MRI scanner to the QIBA Diffusion Pro" by Madeline E. Carr, Kathryn E. Keenan et al.

Purpose: To assess the technical performance of the apparent diffusion coefficient (ADC) on a dedicated 3T radiotherapy scanner, using a standardized phantom and sequences. Investigations into factors that could impact the technical performance of ADC in the clinic were also completed, including changing the slice-encoded imaging direction and the reference sample ADC value. Methods: ADC acquisitions were performed monthly on an isotropic diffusion phantom over 1 year. Measurements of ADC %bias, coefficients of variation for short-/long-term repeatability and precision (CVST/CVLT and CVP), and b-value dependency (Depb) were calculated. The measurements were then assessed according to the Quantitative Imaging Biomarker Alliance (QIBA) Diffusion Profile specifications. Results: The average of all measurements over the year was within Profile recommended ranges. This included when testing was performed in different imaging directions, and on samples that had different ADC reference values ....

Quantitative Imaging Biomarker Alliance , Diffusion Profile , Apparent Diffusion Coefficient , Diffusion Weighted Imaging , Quantitative Imaging Biomarker Alliance , Quantitative Magnetic Resonance Imaging ,