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Scientists at Johns Hopkins Medicine say they have developed a computer model -; dubbed quantitative fate mapping -; that looks back in the developmental timeline to trace the origin of cells in a fully grown organism ....
Credit: Thomas Johnson and Johns Hopkins Medicine In experiments in mouse tissues and human cells, Johns Hopkins Medicine researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged by blinding diseases. The findings are specifically aimed at discovering new ways to reverse vision loss caused by glaucoma and other diseases that affect the optic nerve, the information highway from the eye to the brain. The idea of restoring vision to someone who has lost it from optic nerve disease has been considered science fiction for decades. But in the last five years, stem cell biology has reached a point where it s feasible, says Thomas Johnson, M.D., Ph.D., assistant professor of ophthalmology at the Wilmer Eye Institute at the Johns Hopkins University School of Medicine. ....