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Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis In a new study published in Circulation Research, Chen-Yu Zhang and Xiaohong Jiang's group from Nanjing University and Dongjin Wang's group from Nanjing Drum Tower Hospital reported a critical role of PGC1α in maintaining the contractile phenotype of vascular smooth muscle cells (VSMCs) and highlighted the therapeutic potential of PGC1α for atherosclerosis. The traditional view holds that aberrant proliferation of VSMCs promotes plaque formation after vessel injury and inflammation, whereas the presence of V...

 E-Mail IMAGE: The first measurement of hydroxide conductivity and comparison in anion conducting polymer thin films. (X = OH and Br) view more  Credit: Yuki Nagao from JAIST Ishikawa, Japan - As decarbonization progresses rapidly in the world, fuel cells offer potentially higher electrical efficiency than conventional power-generating systems. Anion exchange membrane fuel cells offer advantages of using non-precious metal catalysts than proton exchange membrane fuel cells. One of the challenges of this next-generation fuel cell is to clarify the hydroxide ion conductivity in the io...