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EXPLAINED: What is Switzerland's animal testing referendum all about?

EXPLAINED: What is Switzerland's animal testing referendum all about?
thelocal.ch - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelocal.ch Daily Mail and Mail on Sunday newspapers.

Renato Werndli , Yves Fluckiger , Samia Hurst , Pierre Bonnaventure , Doron Merkler , Patrycja Nowak Sliwinska , University Of Geneva , Professor Doron Merkler ,

Colder Temperature Eases Inflammation, MS Severity in Mouse Model

Colder Temperature Eases Inflammation, MS Severity in Mouse Model
multiplesclerosisnewstoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from multiplesclerosisnewstoday.com Daily Mail and Mail on Sunday newspapers.

Doron Merkler , Mirko Trajkovski , University Of Geneva ,

Multiple Sclerosis Symptoms Ease at Cold Temperatures in Mice

Scientists at the University of Geneva (UNIGE) showed that colder temperatures provoke a trade-off of energy resources between autoimmunity and thermogenesis in mice. Cold decreases the antigen-presenting protein major histocompatibility complex class II (MHCII) on monocytes at steady state and in various inflammatory conditions including in a mouse model of multiple sclerosis. In addition, cold suppresses T-cell priming and pathogenicity against the body’s own antigens through the modulation of monocytes, thereby reducing neuroinflammation in mouse models of multiple sclerosis. ....

Doron Merkler , Mirko Trajkovski , University Of Geneva , Diabetes Centre , Centre For Inflammation Research , Cell Metabolism , Exposure Protects , Inflammation Research ,

Scientists show how cold could alleviate multiple sclerosis symptoms

In evolutionary biology, the "Life History Theory", first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction. ....

Doron Merkler , Mirko Trajkovski , Emily Henderson , Diabetes Centre At Faculty Of Medicine , Department Of Pathology , University Of Geneva , Centre For Inflammation Research , Department Of Cellular Physiology , Cell Metabolism , Cellular Physiology , Diabetes Centre , Inflammation Research , Multiple Sclerosis , Autoimmune Disease , Cell Metabolism , Central Nervous System , Immune Response , Immune System , Nervous System ,

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model
Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity.
Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, in which nerve cells are attacked by the patient s own immune system. In many cases, the disease develops into a progressive form, which is characterized by a shift of pathology from the white matter to the gray matter, for instance to the cerebral cortex. ....

Martin Kerschensteiner , Doron Merkler , Emily Henderson , Doron Merkler University Of Geneva , Thomas Misgeld Technical University Of Munich , University Of Geneva , Institute For Clinical Neuroimmunology , Clinical Neuroimmunology , Thomas Misgeld , Technical University , Multiple Sclerosis , Central Nervous System , Immune System , Inflammatory Disease , Mouse Model , Nervous System , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஜிநீவ , தொழில்நுட்ப பல்கலைக்கழகம் , பல ஸ்க்லரோசிஸ் , மைய பதட்டமாக அமைப்பு , நோய் எதிர்ப்பு சக்தி அமைப்பு , அழற்சி நோய் , சுட்டி மாதிரி , பதட்டமாக அமைப்பு ,