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Less severe, and that's one of the reasons why the president in his remarks yesterday spoke about how we are going to supplement the capability of hospitals to respond to the possibility that there might be a run on the need for hospitalization. next slide. now, let's talk about some of the immune invasion, we have mentioned this in briefings before. just to reiterate. there's no doubt that there's a marked reduction in neutralizing activity against omicron when you look at the two dose mrna vaccines. when you compare omicron to earlier variants such as delta. however, and here again, why we e...

Has a lot of people feeling optimistic about the new vermont, including doctor anthony fauci. >> the pfizer data gives us now very important information, that although this diminution of the effect of a two dose vaccine, when you get a booster, you dramatically increase the level of projected protection by about 25 fold. which means that people who get boosted after their two dose mrna should really do quite well. that's why we're projecting that we will see clinically. >> yes, that's very good news but it's still early, very early, and lots of people have been boosted. the new variant is only...

If you look at the levels, for example, an antibody, a neutralizing antibody, peaked following the second dose of a two dose mrna. it's at this level. if you look at the peak following the third shop boost, it goes way up here. people ask why is that important? because our experience with variants like the delta variant is that even though the vaccine is not specifically targeted for the delta variant, when you get a high enough level of an immune response, you could spill over protection even against a variant that the vaccine was not specifically directed at and that is why we feel that even...

Antibody peak following the second dose of the two dose mrna, it's like at this level. if you look at the peak following the third shot boost, it goes way up here. >> reporter: nearly 30% of americans who are eligible have gotten a booster shot and demand is surging with concerns about the omicron variant. >> we were kind of a little bit lazy and didn't get our appointments set up yet, so this kind of pushed us forward. >> reporter: while there is plenty of supply in the pipeline, some pharmacies temporarily running out. >> i got a text, "your appointment has been canceled." >> yeah, now the f...

Vaccinated. what is the science telling us with the recommendation this is a moving target whether or not fully vaccinated people can transmit this variant, and are we likely to see break through cases no matter which flavor vaccine you got? >> from studies in israel and the uk, the level of protection of the two dose mrna vaccines, pfizer, biontech and moderna as well, it is lower against actual documented infection cases, around 64%, israel around 80% in england and scotland, robust against serious infection. almost all break through cases are likely not to be serious infections. the questio...