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AACR-NCI-EORTC 2023: From glycobiology to novel immunotherapeutic approaches - Vimarsana News

AACR-NCI-EORTC 2023: From glycobiology to novel immunotherapeutic approaches

Increasing knowledge of the cancer glycome and the need for new options to overcome resistance to immune checkpoint inhibitors are leading to an expansion of glycoimmunology. Stanford University professor Carolyn Bertozzi demonstrated that cell-surface glycans may be tagged to become targetable glyco-immune checkpoints.

Dr Luke on Initial Data From the GLIMMER-01 Trial of E-602 in Advanced Solid Tumors - Vimarsana News

Dr Luke on Initial Data From the GLIMMER-01 Trial of E-602 in Advanced Solid Tumors

Jason J. Luke, MD, FACP, discusses initial results from the phase 1 GLIMMER-01 trial of E-602 in advanced solid tumors.

Palleon Pharmaceuticals and Henlius Enter into Strategic Collaboration to Develop Bifunctional Sialidase Therapies - Vimarsana News

Palleon Pharmaceuticals and Henlius Enter into Strategic Collaboration to Develop Bifunctional Sialidase Therapies

Palleon and Henlius to co-develop Bifunctional HER2-Sialidase and a second bifunctional sialidase to be jointly designed - Henlius received exclusive license for two products in China (including Hong Kong, Macau, and Taiwan); Palleon retains all other global rights - Palleon receives upfront payment and is eligible for up to $196.5 million in milestone payments - SHANGHAI, June 28, 2022 /PRNewswire/ --Palleon Pharmaceuticals Inc., a companypioneering the field of glyco-immunology to treat cancer and inflammatory diseases, todayannounced a strategic collaboration with Shanghai Henlius Biotech, ...

Related Topics:
Hong KongWenjie ZhangJim BroderickShanghai Henlius Biotech IncPalleon Pharmaceuticals IncPalleon PharmaceuticalsShanghai Henlius BiotechGlyco Ligand EditingChief Executive OfficerExecutive DirectorNew Drug ApplicationsGood ManufacturingXuhui PlantSongjiang First PlantPalleon And Henlius To Co Develop Bifunctional Her2 Sialidase Anda Second Be Jointly Designed Received Exclusive License For Two Products In China Including Hong KongNd Taiwan Palleon Retains All Other Global Rights Receives Upfront Payment And Is Eligible For Up To 196 5 Million In Milestone Payments ShanghaiJune 28022 Prnewswire Palleon Pharmaceuticals Inc A Companypioneering The Field Of Glyco Immunology To Treat Cancer And Inflammatory DiseasesOdayannounceda Strategic Collaboration With Shanghai Henlius BiotechNc 2696 Hk To Develop Andcommercialize Two Bifunctional Sialidase Programs From Palleon 39s Eagle Enzyme Antibodyglyco Ligand Editing Immuno Oncology PlatformNcluding Palleon 39s Bifunctional Her2 Sialidasenow In Preclinical Development Anda Second Sialidase To Be Developed With Aproprietary Target Provided By Henlius Eagle Platform Potentiates Antitumor Immunity Enzymatically Removing Immunosuppressive Sialic Acids From Tumor And Immune Cell Surfaces The Is Created Genetic Fusion Of An Engineered Human Antibody DomainsNd Includes Clinical Stage Bi SialidaseS Well As Various Bifunctional Sialidases Comprisinga Sialidase Together Witha Targeting Arm One Of Palleon 39s Most AdvancedHe Bifunctional Her2 Sialidase Has Shown The Potential To Treat Both Low And High Expressing Tumors With Modest Levels Of Tumor Surface Sialoglycans