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Computational tools reveal how blood enzyme works at the atomic level

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism. ....

San Diego , United States , University Of California San Diego , Edwarda Dennis , Varnavasd Mouchlis , Emily Henderson , Proceedings Of The National Academy Sciences , Uc San Diego School Of Medicine , California San Diego School , National Academy , Distinguished Professor , Diego School , Cardiovascular Disease ,

Computer Simulations of Blood Enzyme Could Help To Treat Cardiovascular Disease

Researchers have used state-of-the-art experimental and computational tools to reveal the mechanism of action and substrate specificity of lipoprotein-associated phospholipase A2, a biomarker for cardiovascular disease. ....

San Diego , United States , University Of California San Diego , Edwarda Dennis , Varnavasd Mouchlis , Proceedings Of The National Academy Sciences , Uc San Diego School Of Medicine , California San Diego School , National Academy , Distinguished Professor , Diego School ,

Computer Model of Blood Enzyme May Lead to New Drugs for Cardiovascular Disease

Membrane-associated proteins play a vital role in a variety of cellular processes, yet little is known about the membrane-association mechanism. ....

San Diego , United States , University Of California San Diego , Jian Cao , J Andrew Mccammon , Daiki Hayashi , Edwarda Dennis , Varnavasd Mouchlis , Alexism Vazquez , Proceedings Of The National Academy Sciences , National Institutes Of Health , Uc San Diego School Of Medicine , California San Diego School , National Academy , Distinguished Professor , Diego School , National Institutes ,