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European Approval Sought for Amivantamab Plus Chemo in EGFR Exon 20 Insertion+ NSCLC

A Type II extension of indication application seeking the approval of amivantamab in combination with carboplatin and pemetrexed for the frontline treatment of adult patients with advanced non–small cell lung cancer and activating EGFR exon 20 insertion mutations has been submitted to the European Medicines Agency.

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Janssen Cilag Gmb , Martin Vogel , Kiran Patel , Janssen Research Development , European Medicines Agency For Rybrevant , European Medicines Agency , Drug Administration , Janssen Pharmaceutical Companies Of Johnson , European Commission , Area Lead Oncology , Janssen Cilag Gmbh , Janssen Research , Janssen Pharmaceutical Companies , Epidermal Growth Factor Receptor , Egfr Exon 20 Insertion Mutation , Non Small Cell Lung Cancer Nsclc ,

Takeda to Voluntarily Withdraw Mobocertinib for EGFR Exon 20 Insertion+ NSCLC

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats. ....

United States , Awny Farajallah , Global Medical Affairs Oncology At Takeda , Takeda Pharmaceutical Company , Global Medical Affairs Oncology , North America , Middle East , Non Small Cell Lung Cancer , Lung Cancer , Egfr Exon 20 Insertion Mutation ,

Amivantamab Provides Long-term Clinical Benefit in Post-Platinum EGFR Exon 20 Insertion+ NSCLC

Amivantamab continued to be tolerable and efficacious in patients with non–small cell lung cancer harboring EGFR exon 20 insertion mutations whose disease progressed on platinum-based chemotherapy. ....

Pilar Garrido , Daiichi Sankyo , University Hospital Ram , Boehringer Ingelheim , Oncology Department , Bristol Myers Squibb , European Lung Cancer Congress , Lung Cancer , Universidad De Alcal , Thoracic Tumours Section , Medical Oncology Department , Lung Cancer Congress , Epidermal Growth Factor Receptor , Egfr Exon 20 Insertion Mutation , Non Small Cell Lung Cancer ,