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New antibiotic kills pathogenic bacteria, spares healthy gut microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture. ....

United States , Paul Hergenrother , Jessica Holmes , Matt Sinclair , Rebecca Ultrich , Emad Tajkhorshid , Michelle Hassel , Chao Wen , Hyang Yeon Lee , Royj Carver Biotechnology Center , Centers For Disease , University Of Illinois Urbana Champaign , Disease Control , Antibiotic Resistance Threats , Illinois Urbana Champaign , Chris Fields , Biotechnology Center , Po Chao Wen ,

Nothing is everything: How hidden emptiness can define the usefulness of filtration materials

Nothing is everything: How hidden emptiness can define the usefulness of filtration materials
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United States , University Of Illinois , Qian Chen , Ying Li , Jeffrey Moore , Charles Schroeder , Emad Tajkhorshid , Falon Kalutantirige , Xiao Su , University Of Illinois Urbana Champaign , Nature Communications , University Of Wisconsin , Illinois Urbana Champaign ,