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Date Time Synthetic “micro lungs” could take COVID-19 research to next level 3D cell cultures resembling lung buds. In the real embryo, the green cells would give rise to airways while the red cells would become alveoli. When SARS-CoV-2 began its furious spread around the globe, it took scientists only a few months to develop the first tools to study or neutralize the virus. What’s been missing until now, however, are reliable methods to pinpoint the disease-not the pathogen per se, but the complex biological events playing out inside infected human cells and tissues. Research aimed to ...

Advanced Knowledge on Autism, Basing on Mosaic Mutations by Angela Mohan on  January 12, 2021 at 5:31 PM Mosaic mutations arising during embryonic development could lead to the development of autism spectrum disorder (ASD), as per two studies published in Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS). The findings open new areas for exploring the genetics of ASD and could eventually inform diagnostic testing. Mosaic mutations affect only a portion of a person's cells. Rather than ...

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects Congenital heart defects are the most common type of birth defect, affecting nearly 1% of births in the United States each year, according to the Centers for Disease Control. Doctors have been unable to lower that number due to a lack of knowledge about their source. Thanks to a $2.1 million grant from the National Institutes of Health, an interdisciplinary team of researchers will work to advance the understanding of causes of birth defects. The team includes principal investigator (PI) Lisa Manning, the W...

It is estimated that the majority of pregnancies that fail do so within the first seven days after fertilization, before the embryo implants into the...

You've already lost 50% of your brain cells. it's very difficult for any treatment to be effective at that point. >> but what if you could spot the disease 5, 10, even 20 years before you became symptomatic? he says he may have found a way by looking at the eyes into the brain. >> normally we don't think of the eye as an extension of the brain, but during the embryonic development, the retina actually develops from the brain itself, so it's brain tissue. >> one telltale sign of alzheimer's is a build-up of sticky plaques called beta amyloids. they're inside the brain. they could start to devel...