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New statistical tool improves the ability to find genetic variants that cause disease

A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. ....

Matthew Stephens , Ralphw Gerard , University Of Chicago , Nature Genetics , Associate Professor , Human Genetics , Transcriptome Wide Association , Ene Expression ,

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital). ....

David Liu , Xianqun Fan Department Of Ophthalmology , Science China , Xianqun Fan , Shanghai Jiao Tong University School , Medicine Affiliated Ninth People , Genome Editing , N Vitro , Reverse Transcriptase ,

Mutation butterfly effect: Study reveals how single change triggers autism gene network

Researchers in the RIKEN Center for Brain Science (CBS) examined the genetics of autism spectrum disorder (ASD) by analyzing mutations in the genomes of individuals and their families. ....

Atsushi Takata , Brain Science , Cell Genomics , Stem Cells , Whole Genome Sequencing ,

New Tool Enhances Precision in Uncovering Disease-Causing Genes

New tool integrates GWAS data with genetic expression predictions, enhancing accurate identification of disease-related genes and variants. ....

Matthew Stephens , Ralphw Gerard , Single Genetic Variations , Disease Causation , Associate Professor , Human Genetics , Transcriptome Wide Association , Genetic Variants , Dentify Diseases ,

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability. ....

Santa Catarina , United States , National Center , Image Credit , South America , Biotechnology Information , European Nucleotide Archive , Supplementary Table , New World , Antibiotic Resistance ,