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ASH 2023: Equity, Sickle Cell, and Real-Life Outcomes

Health equity, sickle cell disease, and the thoughtful use of artificial intelligence and social media are among the key themes to be presented at the annual meeting of the American Society of Hematology.

United-states , San-diego , California , Canada , Americans , American , Roberta-brodsky , Mikkaela-sekeres , Cynthiae-dunbar , National-heart , American-society-of-hematology

Promising First Results With DNA Editing to Lower LDL

The first-in-human HEART-1 trial of in vivo DNA editing called VERVE-101, shows reductions in LDL and PCSK9 protein in patients with familial hypercholesterolemia.

Philadelphia , Pennsylvania , United-states , American , Andrew-bellinger , Karol-watson , Amgen , Novartis , American-heart-association , Verve-therapeutics , American-heart , Lipids

International Center for Genetic Disease, Mass General

Collaboration between the International Center for Genetic Disease and the Department of Health – Abu Dhabi, advances state-of-the-art precision medicine...

United-arab-emirates , International-center , Massachusetts , United-states , Boston , Homaid-al-shimmari , John-oreilly , Noura-al-ghaithi , Alireza-haghighi , Abu-dhabi , Mansoor-ibrahim-al-mansoori , Robert-sd-higgins

Placental Cell Disruption Tied to Adult Depression, CVD

Disruption of placental Hofbauer cell function caused by prenatal infection or preterm birth may increase the risk for depression and cardiovascular disease in adulthood.

Montreal , Quebec , Canada , New-york , United-states , Eamon-fitzgerald , Deepakl-bhatt , Nature-communications , Icahn-school-of-medicine-at-mount-sinai , Mcgill-university , Medscape-medical , United-kingdom-biobank

Are We Ready for Systematic Newborn Genome Sequencing?

Routine sampling and analysis of newborn DNA would enable screening for hundreds of childhood genetic diseases, but also raises concerns about privacy and ethics.

Italy , Belgium , Philadelphia , Pennsylvania , United-states , Boston , Massachusetts , New-york , United-kingdom , Paris , France-general- , France