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Novel Research Shows Promise for Tuberculosis Treatment Innovation

Tuberculosis (TB) is the world’s deadliest bacterial disease and most commonly affects the lungs. Recent years have seen an increase in drug-resistant TB cases leaving many patients with limited treatment options. The only vaccine - BCG - is relative

Dublin , Ireland , Joseph-keane , Ahmad-bahlool , Sally-ann-cryan , Mary-osullivan , Health-sciences , European-journal-of-pharmaceutical-sciences , Trinity-college-dublin , Trinity-translational-medicine-institute , University-of-medicine , School-of-pharmacy-biomolecular-sciences

Researchers propose host-directed therapy to stimulate immune system to eliminate tuberculosis

Researchers propose host-directed therapy to stimulate immune system to eliminate tuberculosis
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Dublin , Ireland , Ahmad-bahlool , Sally-ann-cryan , Ahmadz-bahlool , Joseph-keane , Mary-osullivan , Trinity-translational-medicine-institute , Tb-immunology-research-group , Trinity-college-dublin , School-of-pharmacy-biomolecular-sciences , Trinity-college

CN Bio and Altis Biosystems Partner to Develop Next-generation Human Gut/Liver in vitro model for Advanced ADME Studies

CN Bio and Altis Biosystems Partner to Develop Next-generation Human Gut/Liver in vitro model for Advanced ADME Studies
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Yassen-abbas , Lily-jeffery , Ben-scruggs , Altis-biosystems , Stefan-klotter , Bio-physiomimix , Cn-bio-contract-research-services , European-journal-of-pharmaceutical-sciences , Altis-biosystems-inc , Contract-research-services , Repligut-planar , Gut-planar

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptake is Significantly More Impaired than Previously Understood

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptake is Significantly More Impaired than Previously Understood
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Charlotte-wray , Kerstin-hasselgren , Bristol-myers-squibb , European-journal-of-pharmaceutical-sciences , Drug-administration , Per-anderson , Pharmacodynamic-biomarkers , Animal-models-predict-optimal-clinical , H-dependent-solubility , Achilles-heel , Clin-pharmacol-ther , Gastrointestinal-simulator

Xspray Pharma AB: DASYNOC Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL Uptake is Significantly More Impaired than Previously Understood

Xspray Pharma AB: DASYNOC Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL Uptake is Significantly More Impaired than Previously Understood
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Charlotte-wray , Kerstin-hasselgren , Bristol-myers-squibb , European-journal-of-pharmaceutical-sciences , Hynap-technology , Drug-administration , Per-anderson , Pharmacodynamic-biomarkers , Animal-models-predict-optimal-clinical , H-dependent-solubility , Achilles-heel

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptak

 DASYNOC (Xspray’s low dose, amorphous, non-crystalline, dasatinib) avoids interactions with proton pump inhibitors (PPIs), making it potentially the first and only dasatinib to provide patients the full therapeutic benefit of their treatmentSPRYCEL (crystalline dasatinib) uptake, when used with omeprazole, provides...

Charlotte-wray , Kerstin-hasselgren , Bristol-myers-squibb , European-journal-of-pharmaceutical-sciences , Drug-administration , Xspray-pharma , Per-anderson , Pharmacodynamic-biomarkers , Animal-models-predict-optimal-clinical , H-dependent-solubility , Achilles-heel , Clin-pharmacol-ther