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Managing the rise in STIs among older adults

A new research review presented at a pre-congress day for this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, 27-30 April) will look at how to manage the rise in sexually transmitted infections (STIs) in older people, such as gonorrhea, syphilis, and genital warts.

Sweden , Warsaw , L67- , Poland , Kenya , Botswana , United-states , China , Barcelona , Comunidad-autonoma-de-cataluna , Spain , Swedish

Even Slight Rise in One Gut Microbe Might Keep You Out of the Hospital

Even Slight Rise in One Gut Microbe Might Keep You Out of the Hospital
usnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from usnews.com Daily Mail and Mail on Sunday newspapers.

Netherlands , Amsterdam , Noord-holland , Barcelona , Comunidad-autonoma-de-cataluna , Spain , Finland , Dutch , Finnish , Dennis-thompson-healthday , Robert-kullberg , Los-angeles

Harnessing artificial intelligence for infectious disease prevention

A new research review to be given at a pre-congress day for this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) will look at the many ways artificial intelligence can help prevent infectious disease outbreaks including ensuring staff wear personal protective equipment correctly and managing day-to-day hospital activities such as medication prescription and cleaning.

Ireland , Dublin , Irish , Royal-college-of-surgeons , European-congress , European-society-of-clinical-microbiology , Frontiers-in-public-health , Nature-communications , Sepsis-reference-laboratory , Clinical-microbiology , Infectious-diseases

A novel antibiotic class targeting the lipopolysaccharide transporter

Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a major global pathogen with limited treatment options1. No new antibiotic chemical class with activity against A. baumannii has reached patients in over 50 years1. Here we report the identification and optimization of tethered macrocyclic peptide (MCP) antibiotics with potent antibacterial activity against CRAB. The mechanism of action of this molecule class involves blocking the transport of bacterial lipopolysaccharide from the inner membrane to its destination on the outer membrane, through inhibition of the LptB2FGC complex. A clinical candidate derived from the MCP class, zosurabalpin (RG6006), effectively treats highly drug-resistant contemporary isolates of CRAB both in vitro and in mouse models of infection, overcoming existing antibiotic resistance mechanisms. This chemical class represents a promising treatment paradigm for patients with invasive infections due to CRAB, for whom current treatment options are inadequate, and additionally identifies LptB2FGC as a tractable target for antimicrobial drug development. A tethered macrocyclic peptide antibiotic class described here—which shows potent antibacterial activity against carbapenem-resistant Acinetobacter baumannii—blocks the transport of bacterial lipopolysaccharide from the inner membrane to its destination on the outer membrane through inhibition of the LptB2FGC complex.

United-states , Italy , Greece , Karakonstantis , Perifereia-voreiou-aigaiou , Spain , American , America , Infectious-diseases-society-of-america , European-society-of-clinical-microbiology , Drug-administration

Government says no Mycoplasma pneumonia cases detected so far, amid global concerns over resurgence

Clarifies that 7 cases identified during AIIMS study are not connected to the recent increase in respiratory infections among children in other parts of the world, including China

Delhi , India , New-delhi , China , United-states , American , Poonam-sidana , Randeep-guleria , India-institute-of-medical-sciences , Study-group-for-mycoplasma , European-society-of-clinical-microbiology , Department-of-microbiology

Listeria: Who is most susceptible? What are the Symptoms? What are the complications?

With likely all 11 reported Listeria cases linked to peaches hospitalized, what is happening to them? Who is most susceptible to Listeria infection?

European-society-of-clinical-microbiology , Aerosolized-listeria , European-society ,

Time to Treat the Climate and Nature Crisis as One Indivisible Global Health Emergency | Global Health | JAMA

Over 200 health journals call on the United Nations, political leaders, and health professionals to recognize that climate change and biodiversity loss are one

Belgium , Turkey , Montreal , Quebec , Canada , Dubai , Dubayy , United-arab-emirates , Chris-zielinski , Eli-lilly , A-global-health-emergency , Astrazeneca

Mask Mandates Back in Hospitals Across Canada Just Months After Being Removed

Mask Mandates Back in Hospitals Across Canada Just Months After Being Removed
theepochtimes.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from theepochtimes.com Daily Mail and Mail on Sunday newspapers.

United-kingdom , Montreal , Quebec , Canada , Denmark , Copenhagen , Køavn- , Smiths-falls , Ontario , Perth , Western-australia , Australia